Infants born with KCNQ2-EE experience not only frequent seizures, but also profound developmental delay, and sometimes early death
Developmental & Epileptic Encephalopathy Diagnosis
Children with DEE experience persistent seizures, which often respond poorly to treatment.
DEE is associated with varying degrees of decreased alertness, poor muscle tone, and developmental impairment involving one or more domains (motor, social, language, cognition).
Brainwave patterns show evidence of seizure activity as well as abnormal patterns between seizures, particularly in the first year of life.
Several genetic variants distinguish DEE from other childhood epilepsies.